Articles / The BRACE trial & off-target benefits of vaccines

This week’s expert:
Dr Rama Kandasamy, Paediatrician, Sydney Children’s Hospital; NHMRC Emerging Leader Fellow; Conjoint Lecturer, Infectious Diseases Research, UNSW
Drawn from Dr David Lim’s interview with Dr Rama Kandasamy on the Healthed Podcast, ‘Going Viral’.
• There is evidence, from epidemiological data, that vaccines may have some beneficial off-target effects that is, may confer protection against other diseases beyond the infection targeted by the vaccine
• Specifically, there is evidence that populations who have had BCG and measles vaccination subsequently have fewer hospitalisations for respiratory infections than unvaccinated populations

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Very overestimated
Moderately/slightly overestimated
Quite accurate
Moderately/slightly underestimated
Very underestimated
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