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Dr Linda Calabresi

Hormone replacement therapy has recently hit the headlines again and not in a good way. A research paper published in The Lancet reignited the controversy by again highlighting an association between hormone therapy and breast cancer. While the experts have been quick in their response, pointing out the numerous limitations of the study and the researchers’ conclusions, it is still more than likely GPs will again be grilled about the latest evidence with regard to this treatment. It’s an area of medicine that certainly has been heavily scrutinised over the past couple of decades and as such it is important GPs have ready access to the latest guidelines to best practice. Here is a great little resource that fits the bill perfectly.

Kassia Beetham

Expectant mothers receive an avalanche of information about potential risks to their baby. There’s a growing list of foods, toxins and environmental threats to avoid. It’s normal for this to lead to an increased level of anxiety. As a result, some women believe it’s safer to avoid any risks in pregnancy, no matter how small. Vigorous exercise may be considered one of these risks. But we’ve recently reviewed the research and found vigorous exercise is safe during pregnancy, including in the third trimester. And not only is it safe; it’s healthy, too.

Dr Linda Calabresi

Even primary school children know a good diet and proper nutrition is important if you want to be physically healthy. Eat the wrong things or insufficient of the good things and chances are you’re destined to develop heart problems, diabetes or cancer. But what about a person’s psychological health? How important is diet and nutrition in mental health? And is there any evidence that people treat or prevent mental illness by taking particular nutrients, supplements or vitamins?

Dr Linda Calabresi

Recognise this scenario? You prescribe an inhaler for the patient. You educate the patient on why they need the inhaler. You draw diagrams. You demonstrate the technique on the placebo inhaler. You write the script. And then… you cross your fingers.

Dr Linda Calabresi

Endovenous laser ablation has been rated as the most successful and cost-effective treatment for varicose veins over surgery and sclerotherapy, according to recent research. In a UK randomised controlled trial involving almost 800 patients, researchers analysed quality of life questionnaires completed by trial participants five years after having their varicose veins treated via one of these methods. “This large, multicentre trial … showed that in all three groups, quality of life five years after treatment was improved from baseline,” the study authors wrote in The New England Journal of Medicine.

Dr Linda Calabresi

Screening for prostate cancer with PSA testing has always been a bit controversial. Initially the high rate of false positives, especially in younger men, had most GPs questioning whether overall, we were doing more harm than good. But it would seem we’ve come a long way since those early days. Not only do we understand a lot more about the PSA test itself, but also, we now are better able to determine what an elevated PSA signifies in a particular patient through tools such as imaging, before subjecting the man to a series of invasive procedures.

Prof Martha Hickey

Menopause is a normal life stage for women at around 51 years. Most women don’t need treatment for their symptoms, but around 13% of Australian women aged 50-69 take menopausal hormone therapy (sometimes called “hormone replacement therapy”). This medication contains hormones that are normally low or absent after menopause, and reduces symptoms such as hot flushes and night sweats, which can be troublesome and persistent for some women. But growing evidence over recent years has pointed to an increased risk of breast cancer associated with menopausal hormone therapy. This has already led some women to stop or avoid the treatment.

Dr Linda Calabresi

While the ‘opioid epidemic’ might be grabbing all the headlines at the moment, Australian toxicologists are reminding us that paracetamol is the most common drug used in overdoses in this country. What’s more the numbers of both paracetamol-related hospital admissions and liver injury have been increasing over the past decade at a rate that far exceeds the rate of population increase. According to a retrospective study recently published in The Medical Journal of Australia, there has been an average 3.8% annual increase in the number of paracetamol-related hospital admissions since 2007, and a mean 7.7% annual increase in paracetamol-related liver injury cases, whereas the population has been increasing at a rate of only 1.6% annually.

Dr Linda Calabresi

Any doctor who has done the online yellow fever vaccination training module on the ACRRM website will be aware of this resource. It’s a straight-forward, one-page pdf that presents a set of questions you need to ask the patient to see whether there are any contraindications to them receiving the yellow fever vaccination or indeed any live vaccine. The checklist has been derived from information in the Australian Immunisation Handbook, and it is both succinct and comprehensive.

Dr Linda Calabresi

Want your best chance for living a long, healthy life? Have a diet that is high in plant protein, say Japanese researchers. That’s the suggestion following their prospective study of over 70,000 adults, recently published in JAMA Internal Medicine. According to their findings, a higher intake of plant protein was associated with lower total mortality, specifically mortality related to cardiovascular disease. In fact, those people whose diet was proportionally in the highest bracket for plant protein were up to 41% less likely to die from a heart attack or stroke.

Dr Lawrie Bott

Glomerular filtration rate (GFR) is the best single measure of kidney function. A subnormal GFR is an important early indicator of possible chronic kidney disease. However, it also does not identify the cause. It is also not a ‘catch all’, for example, in early diabetes mellitus, GFR will typically be normal or even increased, due to ‘hyperfiltration’. Optimal detection and risk stratification of early kidney disease also requires measurement of urine albumin, rather than just eGFR.

Dr Vivienne Miller

General Practitioner Dr Vivienne Miller takes a look at what’s changed in the recently updated CHA2DS2-VASC Score for the determination of stroke risk factors from atrial fibrillation. The CHA2DS2-VA Score was updated from the CHA2DS2-VASC Score last year to exclude female sex (represented by Sc) in the determination of stroke risk factors from atrial fibrillation. The two scores are identical, apart from the exclusion of female sex, which is no longer considered an outright risk factor in stroke from atrial fibrillation, but more of a ‘risk modifier’ of this complication.1General Practitioner Dr Vivienne Miller takes a look at what’s changed in the recently updated CHA2DS2-VASC Score for the determination of stroke risk factors from atrial fibrillation. The CHA2DS2-VA Score was updated from the CHA2DS2-VASC Score last year to exclude female sex (represented by Sc) in the determination of stroke risk factors from atrial fibrillation. The two scores are identical, apart from the exclusion of female sex, which is no longer considered an outright risk factor in stroke from atrial fibrillation, but more of a ‘risk modifier’ of this complication.